Virtual Storage Console for VMware vSphere
This article describes on how to identify misalignment over NFS on the storage system.
Misalignment of I/O is possible over LUNs and NFS mounts (using virtualization products).
At a basic level, misalignment is when a host improperly lays blocks on the storage system, which causes partial writes.
For more information on misaligned I/O, see the following links.